MSDS for 1-Bromo-3-Methylbutane

Identification

Product Name: 1-Bromo-3-Methylbutane
Chemical Formula: C5H11Br
CAS Number: 107-82-4
Synonyms: Isoamyl bromide, Isopentyl bromide
Recommended Use: Organic synthesis, laboratory solvent, intermediate for pharmaceuticals and flavors
Manufacturer/Supplier: Information available on product label and purchase documents
Emergency Phone Number: Listed on label or SDS provided by supplier
Contact Information: Refer to company documentation for address and contact details

Hazard Identification

Classification: Flammable liquid, harmful if inhaled or swallowed, causes skin and eye irritation
Signal Word: Warning
Hazard Statements: Highly flammable, may cause respiratory tract irritation, harmful to aquatic life with long-lasting effects, may cause damage to the central nervous system and liver with prolonged exposure
Pictograms: Flame, exclamation mark, health hazard
Precautionary Statements: Avoid breathing vapors, use only outdoors or in well-ventilated area, keep away from heat/sparks/open flames, wear protective gloves and eye protection, wash hands thoroughly after handling, avoid release to the environment

Composition / Information on Ingredients

Chemical Name: 1-Bromo-3-Methylbutane
Concentration: ≥98%
Impurities/Additives: Trace levels of related alkyl bromides (<2%)
Molecular Weight: 151.05 g/mol
EINECS Number: 203-525-2

First Aid Measures

Inhalation: Remove to fresh air immediately, seek medical attention if symptoms develop, assist breathing with artificial respiration if necessary
Skin Contact: Rinse skin thoroughly with soap and water for several minutes, remove contaminated clothing, seek medical attention for irritation
Eye Contact: Rinse cautiously with water for several minutes, remove contact lenses if present and easy to do, continue rinsing, seek immediate medical advice
Ingestion: Do not induce vomiting, rinse mouth with water, seek immediate medical attention, provide symptomatic and supportive care
Important Symptoms: Burning sensation, cough, headache, nausea, dizziness, drowsiness, possible respiratory distress, dermatitis with prolonged exposure
Immediate Medical Attention: Always needed for significant exposure, airway protection may be required for inhalation or ingestion

Fire-Fighting Measures

Extinguishing Media: Use dry chemical, carbon dioxide, or alcohol-resistant foam, avoid water jets
Hazards from Combustion: Toxic hydrogen bromide and carbon oxides can form, dense vapors may cause flashes
Protective Equipment: Use self-contained breathing apparatus, full protective clothing, approach fire from upwind side
Specific Hazards: Vapors can form explosive mixtures with air, may flow along surfaces to distant ignition sources
Special Procedures: Cool fire-exposed containers with water spray to prevent rupture, prevent contaminated run-off from entering sewers and waterways

Accidental Release Measures

Personal Precautions: Evacuate area, ventilate, avoid breathing vapors, use personal protective equipment including gloves, goggles, and chemical-resistant clothing
Environmental Precautions: Prevent entry into drains, surface water, and soil, notify local authorities about large spills
Spill Containment: Dike and absorb spill with inert dry material such as sand or vermiculite, collect in suitable containers for proper disposal
Cleanup Methods: Clean area thoroughly with water and detergent after product removal, ventilate area well before reuse

Handling and Storage

Safe Handling: Handle in a fume hood or well-ventilated space, avoid inhalation and direct contact, do not smoke, eat, or drink while using this product, keep container closed when not in use
Storage Requirements: Store tightly sealed in a cool, dry, well-ventilated area away from incompatible substances such as strong oxidizers and acids, keep away from heat and ignition sources
Packaging Materials: Use only containers that are compatible with alkyl bromides, avoid metal containers susceptible to corrosion
Incompatibles: Avoid strong acids, alkalis, oxidizing agents, amines, or strong reducing substances

Exposure Controls and Personal Protection

Exposure Limits: No established OSHA or ACGIH exposure limits; keep airborne concentrations as low as possible
Engineering Controls: Use chemical fume hood, provide local exhaust ventilation, use closed systems where feasible
Personal Protective Equipment: Wear butyl rubber or nitrile gloves, chemical splash goggles, face shield for high splash risk, protective lab coat or apron
Respiratory Protection: Use air-purifying respirators with organic vapor cartridges if ventilation is inadequate or exposure limits may be exceeded
Hygiene Measures: Wash hands thoroughly after handling, do not bring contaminated clothing home, launder work clothing regularly

Physical and Chemical Properties

Appearance: Clear, colorless to pale yellow liquid
Odor: Penetrating, unpleasant, similar to other alkyl bromides
Odor Threshold: Not specified
pH: Not applicable (non-aqueous)
Melting Point: -98°C
Boiling Point: 118-120°C at 760 mmHg
Flash Point: 25°C (closed cup)
Evaporation Rate: Moderate, related to volatility
Flammability: Flammable liquid and vapor
Upper/Lower Flammability: Not readily available
Vapor Pressure: 18 hPa at 20°C
Vapor Density: Heavier than air
Relative Density: 1.228 g/cm³ at 25°C
Solubility: Insoluble in water, soluble in organic solvents like ether and alcohol
Partition Coefficient (n-octanol/water): Log Kow 3.2 (estimated)
Auto-Ignition Temperature: Above 210°C
Decomposition Temperature: Not specified
Viscosity: Not specified

Stability and Reactivity

Chemical Stability: Stable under standard conditions of storage and use
Thermal Decomposition: Risk of toxic product formation above decomposition temperature, hydrogen bromide and carbon oxides likely
Hazardous Reactions: May react vigorously with strong oxidizing agents, acids, alkalis, and amines
Conditions to Avoid: Excessive heat, open flames, static discharge, incompatible substances
Polymerization: Will not occur under recommended conditions
Incompatible Materials: Acids, bases, oxidizers and strong reducing agents

Toxicological Information

Acute Toxicity: Harmful if inhaled, skin contact, or swallowed; LD50 oral (rat) >2000 mg/kg, limited data shows low to moderate toxicity
Skin Corrosion/Irritation: Causes irritation, redness, possible burns with prolonged or repeated contact
Eye Damage/Irritation: Causes eye irritation and temporary vision disturbances
Respiratory Sensitization: Can cause coughing, shortness of breath, headache
Chronic Effects: Repeated exposure may affect liver, kidneys, and central nervous system, possible dermatitis
Carcinogenicity: No current classification, but general guidelines advise caution with alkyl halides
Mutagenicity and Reproductive Toxicity: Limited data suggest low risk, further study may be warranted for workers with regular high exposure

Ecological Information

Toxicity: Harmful to aquatic life with long-lasting effects, estimated LC50 for fish (96h) >100 mg/L
Persistence and Degradability: Not readily biodegradable, slow breakdown in soil or water, persistent bromine compounds may remain
Bioaccumulation: Moderate potential, based on partition coefficient
Mobility in Soil: Can leach into soil and contaminate groundwater, highly mobile in sandy soils
Other Adverse Effects: Avoid uncontrolled release to prevent environmental contamination and long-term build-up

Disposal Considerations

Waste Disposal Methods: Dispose of via licensed hazardous waste contractor, do not pour down drain or mix with general waste
Container Disposal: Rinse containers thoroughly, dispose as hazardous chemical waste, do not reuse for other materials
Contaminated Packaging: Dispose of as chemical waste, observe all local and federal regulations
Environmental Precautions: Prevent release to environment, use secondary containment where appropriate

Transport Information

UN Number: 2342
Proper Shipping Name: 1-Bromo-3-methylbutane
Transport Hazard Class: 3 (Flammable Liquid)
Packing Group: II
Labels: Flammable Liquid
Environmental Hazards: Harmful to aquatic environment; marine pollutant label may apply
Special Precautions: Secure tightly, provide sufficient ventilation, segregate from incompatible loads, keep away from sparks and sources of ignition
Regulations: Subject to ADR, IMDG, and IATA rules

Regulatory Information

TSCA Status: Listed in the Toxic Substances Control Act inventory
DSL Status: Present in Canada’s Domestic Substances List
OSHA Hazards: Flammable, irritant, harmful by inhalation or ingestion
REACH Registration: Required for import to European Union above threshold amounts
Other Regulations: Subject to reporting under SARA Title III Section 313 if stored above threshold; local municipal requirements may vary
Risk Phrases: R10 (Flammable), R36/37/38 (Irritating to eyes, respiratory system, and skin)
Safety Phrases: S16 (Keep away from sources of ignition), S24/25 (Avoid contact with skin and eyes), S29 (Do not empty into drains)
Workplace Labelling: Follow local and federal requirements for chemical labelling and communication